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ProZYM plus

Prolyl Oligopeptase 1,000,000 PPI* plus Holy Thistle extract

To support the body in breaking down stressful proline peptide structures in the intestines, vessels and tissues, strengthening the immune system and stimulating the liver to eliminate unwanted substances

With synergistic effect between natural enzyme and plant compounds


60 capsules (27 g)
Food supplement

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Product Description

ProZYM plus – your natural booster for proline digestion, liver and immune system

Synergistic enzyme product from high-dose prolyl oligopeptidase and selected holy thistle fruit extract

Our carefully designed complex preparation ProZYM plus combines high-dose prolyl oligopeptidase with selected holy thistle fruit extract of the highest quality.

ProZYM plus contains 1,000,000 PPI (Protease Picomole International) of the natural proteolytic (i.e. protein-degrading) enzyme prolyl oligopeptidase. The speciality of prolyl oligopeptidase is the cleavage of particularly resistant proline compounds. Proline is an amino acid that the organism can only cleave and degrade very limited by itself. Proline occurs as “glue protein” in grain gluten and causes various types of intolerance in many people. Experience has shown that a considerable part of the otherwise healthy populations has a limited tolerance for the grain-specific peptide gluten. However, prolyl oligopeptase also digests other proteins, so that it can be used, for example, to improve protein utilisation in a high-protein sports diet or in geriatric persons.

ProZYM plus provides prolyl oligopeptitase for proline cleavage, which is enzymatically active in the universal pH range and can therefore be systemically effective in different compartments of the body, i.e. not only in the intestine, but it can also cleave proline-containing peptide structures in the tissues or in the blood. The complex formulation together with holy thistle or milk thistle is intended to stimulate the power of the liver, which is always involved in the body’s own degradation and excretion processes. Two partners who are therefore ideally made for each other! The combination with lecithin in turn favours the bioavailability of many plant substances for our organism.

Benefit from ProZYM plus with a synergistic effect: Just two capsules daily provide you with peak enzyme activity of 1,000,000 PPI* plus 300 mg of highly concentrated holy thistle extract!

*PPI (Protease Picomole International): indicates the enzyme activity

Prolyl Oligopeptidase & Holy Thistle support the following body’s own metabolic mechanisms:

  • Cleavage of proline-containing peptide structures that are hard to digest, especially gluten in the intestine
  • To complement a ketogenic diet for prevention of coeliac disease or other gluten-sensitive reactions
  • Decomposition of stressful proline peptides, systemically in vessels and tissues
  • Stimulation of liver metabolism
  • Immune support

Groups of people for whom the diet with Prolyl Oligopeptidase & Holy Thistle is particularly recommended:

  • People with digestive and intestinal discomfort
  • People with limited gluten tolerance
  • People who want to stengthen their liver power
  • People with low immunity

Product background

Like many enzymes, prolyl oligopeptidases such as those contained in ProZYM plus have a high specificity and are also produced by a large number of immune-active cells. Prolyl oligopeptidases are found in plant and animal organisms, in fungi and numerous bacteria. It has recently become known that they are also produced by lactobacilli in the human large intestine, which, however, requires a healthy microbiome.

They belong to the large group of serine proteases that are specialised in cleaving smaller prolamine peptides, i.e. short amino acid compounds that are below the size of proteins and contain the amino acid proline, which is hard to digest. Oligopeptidases are also involved in numerous immunological processes. They not only have a digestive effect, but like most proteases, they also have a systemic effect. Like many proteases, they are involved in the regulation of metabolic cascades such as the RAAS mechanism, which is of great importance not only for the regulation of blood pressure and fluid balance, but also, as has only recently become known, for the orchestration of our entire immune defence.

Unique synergy effect
Made in Germany

ProZYM plus is without following substances:

dr. reinwald vital products - without gmo without GMO
dr. reinwald vital products - without animal testing without animal testing
dr. reinwald vital products - without additives without additives
dr. reinwald vital products - without pesticides without pesticides
dr. reinwald vital products - without soy without soy

Prolyl Oligopeptidase & Holy Thistle are good for:

immune system
immune system
immune system

ProZYM plus -provides prolyl oligopeptidase with 1,000,000 PPI (enzymatic units) and strong proteolytic activity

ProZYM plus by dr.reinwald vital

ProZYM plus – with a peak enzyme activity of 1,000,000 PPI* plus 300 mg of highly concentrated holy thistle extract

ProZYM plus by dr.reinwald vital


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ProZYM plus – your advantage over conventional prolyl oligopeptidase OR milk thistle supplements

We are often asked what makes our products stand out from conventional supplements. The answer here is quite simple: it is the quality of the ingredients and of course the synergistic formula with added value! You are not convinced yet? Check for yourself:

ProZYM plus by dr.reinwald vital

ProZYM plus by dr.reinwald vital
Unbeatable formula for maximum effectiveness

  • Our Prolyl Oligopeptidase provides a peak activity and 1,000,000 PPI (Enzymatic Units) per daily dose.
  • We use a Holy Thistle extract of the highest quality. The plant extract ratio is 10:1, which means that a daily amount of 2 capsules of ProZYM provides 300 mg of holistically highly concentrated fruit extract, which corresponds to a plant dry mass of 3 .
  • We fill in gastro-resistant capsule shells in order to allow as much enzyme as possible to unfold only in the small intestine to strengthen the systemic effect.
  • Interacting formulation of substances that complement and activate each other
  • Highly dosed and effective
  • Free from any additives and adjuvants
  • 100 % vegan and 100 % ketogenic
  • Natural, sustainable and without animal testing
  • GMO-free raw materials
  • Organic and therefore bioavailable ingredients of the highest quality
  • Made in Germany n certified manufacturing plants

Products by dr.reinwald vital - your advantage

Conventional prolyl oligopeptidase OR milk thistle supplements – be sure to check before you buy:

  • that the concentration and quality of prolyl oligopeptidase is appropriate.
  • that the milk thistle ingredients are appropriate in concentration and quality.
  • for enteric encapsulation.
  • the formula. Incomplete formulas or mono-products have a lower potency.
  • whether the dosage or daily recommondation is comparable.
  • for excipients, fillers and separating and binding agents as well as substances that have no place in a health product, especially maltodextrin, stearates, lactose, gluten, sugar, purine, iodine, milk, egg, soya, yeast, flavourings, flavour enhancers, preservatives and colourings.
  • if the product is vegan or ketogenic if this is important to you.
  • for synthetic, chemically produced ingredients. Natural ingredients are often not originated from sustainable sources.
  • for possibly genetically modified raw materials.
  • for inorganic ingredients that have very little bioavailability for our organism.
  • the origin. Germany standards are considered number one in the world for quality, ahead of Switzerland and the USA.

ProZYM plus and its cofactors

Our dr.reinwald vital products have been designed as complex formulations. These active complexes are far more efficient than mono-substances, as they provide the organism with the important synergists and cofactors it needs to optimally support the controlled metabolic processes.

ProZYM plus
is also a synergy complex that develops a strong effect through the combination of high-dose prolyl oligopeptidase with highly concentrated holy thistle extract.

Why the combination of Prolyl Oligopeptidase & Holy Thistle?

As an attentive reader, you may have already noticed that both the enzyme and the plant substances of holy thistle interact via various metabolic pathways and, depending on the requirements, are both-as well active, i.e. systemically and not unilaterally.

ProZYM plus provides a proline-specific oligopeptidase that can cleave proline and thus also resistant prolamines such as gluten. This protease is active in the universal pH range and can therefore become effective in different compartments of the body, such as in the intestine, vessels and tissues. The degradation products, especially those from secondary metabolism beyond the intestinal barrier, must be disposed of via the body’s own excretory mechanisms.

The liver plays a key role in all of the body’s detoxification processes. The traditionally known property of holy thistle to strengthen liver metabolism and thereby support the body’s own detoxification has particularly inspired us to bring it together with the enzyme prolyl oligopeptase. The stimulation of our organism’s self-cleansing powers complements the protein-cleaving work of the enzyme, which naturally leaves behind degradation products because the plant substances help to “clean up”. The bioavailability of the plant substances from holy thistle is promoted and optimised through the combination with lecithin.

Due to its special properties, holy thistle is one of many plants that can support a healthy immune response. Especially in combination with the right enzymes such as prolyl oligopeptidase, this combination forms a very good basis for immune strengthening and prevention. Together with vitamin D and a regular elimination of unwanted pollutants, also with the help of Glutathion comp, you can do something very good for the maintenance of his health and immune defence.


Holy thistle fruit extract (Silybum marianum fructi), prolyl oligopeptidase, capsule shell: hydroxypropylmethylcellulose, lecithin

Our prolyl oligopeptidase has peak enzyme activity and is highly dosed at 1,000,000 PPI* per daily recommendation. In addition, we use the highest quality holy thistle extract. The plant-to-extract ratio is 10:1, which means that a daily dose of 2 capsules of ProZYM provides 300 mg of holistic, highly concentrated root extract, which corresponds to 3 g of plant dry matter.

*PPI (Protease Picomole International): indicates the enzyme activity


60 gastro-resistantcapsules (27 g) – sufficient for 30 days

Nutritional values

Nutrients ProZYM plus per 2 capsules
%-information: Nutrient reference value

ProZYM plus by dr.reinwald vital


Recommended consumption

2 capsules daily with good water, 30 minutes before a meal. Especially before meals containing cereals.

Notice: May increase the effect of blood-thinning and anticoagulant drugs.
Suitable for vegans. Suitable for ketogenic diet.

Legal note: This product is for nutrition and therefore does not affect any Drug Act of any country. A good nutritional status can help the organism prevent or to overcome diseases. All statements describe characteristics and physiological effects, which can be different for consumers, and do not constitute a healing or health promise.

Weight 0,059 kg
Dimensions 4,9 × 4,9 × 9,4 cm







Food supplement

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